Researching Options for
STROKE REHABILITATION

See if the Vivistim® Clinical Study is right for you

Each year nearly 800,000 people in the US suffer a stroke. Strokes can occur at any age, and are the leading cause of long-term disability in the United States. For many, a stroke affects mobility of the arms and hands, making it difficult to perform normal, everyday activities.

Right now, doctors at select centers in the U.S. are accepting participants for a new stroke rehabilitation research study. The study is for the Vivistim system, an investigational device designed to restore upper limb movement following a stroke. The Vivistim system pairs a technique known as Vagus Nerve Stimulation (VNS) with rehabilitative exercises, to restore arm and hand function.

If you suffered a stroke at least 9 months ago, but not more than 10 years ago, and struggle with hand and arm movement, the Vivistim Clinical Study may be right for you.

What is Vivistim?

Vivistim is a new, investigational therapy for stroke rehabilitation that builds upon a well-known treatment called Vagus Nerve Stimulation (VNS). The vagus nerve is located in the neck, and is unlike any other nerve in the body. It directly connects to the brain and sends important signals to tell the brain what to learn, and when to learn it.

The Vivistim system uses a small device called a neurostimulator, which is implanted below the skin through a minimally-invasive, outpatient procedure. During the procedure, the Vivistim system is connected to the vagus nerve.

Once the Vivistim system is placed, you will work with a rehabilitation specialist over a series of sessions aimed at rebuilding the motor circuits associated with certain movements. Each time you perform a correct movement, your therapist pushes a button, which sends a wireless signal to the Vivistim device to deliver a mild electrical pulse to the vagus nerve. In this way, the Vivistim system is telling your brain to “pay attention” to that movement. This nerve stimulation may be so mild that you do not even feel it – it just depends on the settings and your tolerance. Over the course of several weeks, these paired therapy sessions are designed to restore arm and hand function.

Why Participate?

Right now, doctors at select centers in the U.S. are accepting participants for a new stroke rehabilitation research study. The study is for the Vivistim system, an investigational device designed to restore upper limb movement following a stroke. The Vivistim system pairs a technique known as Vagus Nerve Stimulation (VNS) with rehabilitative exercises, to restore arm and hand function.

If you qualify and choose to join the Vivistim study, you will receive:

  • The Vivistim system and rehabilitation therapy sessions at no cost
  • All study-related care and medical exams at no cost
  • Compensation for your time and travel to attend study visits



Frequent Questions
Clinical studies (also called clinical trials) are used to learn about the safety and effectiveness of possible new medications, medical devices, and medical procedures. Although there are many types of clinical trials, all must conform to strict rules set by the U.S. Food and Drug Administration (FDA). These rules help protect the rights and safety of those who volunteer to take part in clinical trials.
Yes, Vagus Nerve Stimulation has been used previously in the US and around the world to treat other medical conditions such as epilepsy and depression. The Vivistim system is an investigational device that pairs VNS therapy with rehabilitative exercises, designed to restore upper limb movement following a stroke.
If you join the study, your participation will last up to 3 years. Following your procedure to place the Vivistim system, you will visit your local study center regularly over the next 6 to 12 weeks for your rehabilitation sessions. You will then continue to visit your study center every few months over the first year, and then yearly thereafter. These ongoing visits are an important part of the study, as they allow your doctor and study team to closely monitor how you are doing.
If you choose to join the study, you will receive any study-related care at no cost. This includes the Vivistim system and procedure, as well as rehabilitation therapy sessions and follow-up visits to your local study center. You will also be reimbursed for your time and travel to attend these visits.
The study is being sponsored by MicroTransponder, Inc. (www.microtransponder.com), a medical device company based in Austin, TX..
To see if you might qualify for the study, and to get connected with your local study center to discuss the study further, the next step is taking the pre-screening questionnaire. Please click here to get started.

See If You Qualify

To see if you might qualify for the study, and to get connected with the Vivistim study center in your area to learn more, please take the questionnaire below.